BDBM131725 US8835465, 21

SMILES C[C@H](Nc1nc(Nc2cc([nH]n2)C2CC2)c(Cl)cc1Cl)c1ccc(F)cc1

InChI Key InChIKey=IKAKCCCBVXFBIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 131725   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM131725(US8835465, 21)
Affinity DataIC50: 611nMT: 2°CAssay Description:Trk A kinase activity was measured for its ability to phosphorylate synthetic tyrosine residues within a generic polypeptide substrate using an Ampli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2015
Entry Details
US Patent