BDBM131839 US8835445, 10

SMILES Nc1nc(N)c2cc(Cn3ccnc3)c(cc2n1)-c1ccc(CO)c(CO)c1

InChI Key InChIKey=KHXQSOCPVWGFGA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 131839   

TargetDihydrofolate reductase(Staphylococcus aureus)
Trius Therapeutics

US Patent
LigandPNGBDBM131839(US8835445, 10)
Affinity DataKi:  0.510nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetDihydrofolate reductase(Human)
Trius Therapeutics

US Patent
LigandPNGBDBM131839(US8835445, 10)
Affinity DataKi:  53.6nMAssay Description:Antibacterial activity as measured by the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations of compounds are well known...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent