BDBM13207 (3S,6S,8aS)-6-[(2S)-2-aminopropanamido]-5-oxo-N-phenyl-octahydroindolizine-3-carboxamide::Smac AVPI Mimetic 12a

SMILES C[C@H](N)C(=O)N[C@H]1CC[C@H]2CC[C@H](N2C1=O)C(=O)Nc1ccccc1

InChI Key InChIKey=XZLVUDTWCKTORR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13207   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
University of Michigan

LigandPNGBDBM13207((3S,6S,8aS)-6-[(2S)-2-aminopropanamido]-5-oxo-N-ph...)
Affinity DataKi: >1.00E+5nM ΔG°: >-5.40kcal/molepH: 7.5 T: 2°CAssay Description:A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2007
Entry Details Article
PubMed