BDBM132149 CVD-0005158::JAG-UCB-cedd89ab-1::USRE45173, 88A

SMILES Cc1ccncc1N1CCN(C1=O)c1cccc(Cl)c1

InChI Key InChIKey=ZTWAZISELGQBHC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 132149   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Novartis

US Patent
LigandPNGBDBM132149(USRE45173, 88A | JAG-UCB-cedd89ab-1 | CVD-0005158)
Affinity DataIC50: 12nMAssay Description:Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM132149(USRE45173, 88A | JAG-UCB-cedd89ab-1 | CVD-0005158)
Affinity DataIC50: 8.17E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM132149(USRE45173, 88A | JAG-UCB-cedd89ab-1 | CVD-0005158)
Affinity DataIC50: 8.17E+4nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM132149(USRE45173, 88A | JAG-UCB-cedd89ab-1 | CVD-0005158)
Affinity DataIC50: 9.90E+4nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article