BDBM13224 2-N-benzene-4-methyl-5-N-(2,4,6-trimethylphenyl)-1,3-thiazole-2,5-diamido::BMS-354825 2-Amino-4-methyl-thiazole Analog 7d::CHEMBL130719
SMILES Cc1nc(NC(=O)c2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C
InChI Key InChIKey=LEOANBUEWRQPOF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 13224
Affinity DataIC50: 800nMpH: 7.0 T: 22°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of murine Lck kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibitory activity of the compound human Lck(hLck) kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase LCK(Mouse)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 320nMpH: 7.0 T: 22°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...More data for this Ligand-Target Pair