BDBM132317 US8841312, 63

SMILES C1CCC(C1)n1c2cnccc2c2cnc(Nc3ccc(N[C@@H]4CCNC4)cn3)nc12

InChI Key InChIKey=SMNBJOCPOYEKDE-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132317   

TargetCyclin-dependent kinase 6(Human)
Amgen

US Patent
LigandPNGBDBM132317(US8841312, 63)
Affinity DataIC50:  20nMpH: 7.4 T: 37°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetCyclin-dependent kinase 4(Human)
Amgen

US Patent
LigandPNGBDBM132317(US8841312, 63)
Affinity DataIC50:  3.40nMpH: 7.4 T: 37°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent