BDBM132317 US8841312, 63
SMILES C1CCC(C1)n1c2cnccc2c2cnc(Nc3ccc(N[C@@H]4CCNC4)cn3)nc12
InChI Key InChIKey=SMNBJOCPOYEKDE-MRXNPFEDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 132317
Affinity DataIC50: 20nMpH: 7.4 T: 37°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMpH: 7.4 T: 37°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair