BDBM13398 A313326 Analogue 35::N-(4-{[(4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy]methyl}-3-(3-methoxyphenyl)phenyl)methanesulfonamide
SMILES COc1cccc(c1)-c1cc(NS(C)(=O)=O)ccc1COC(c1cncn1C)c1ccc(cc1)C#N
InChI Key InChIKey=JEUIGZFCGGXISK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 13398
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R and Abbott Laboratories
Globe Pharmaceutical R and Abbott Laboratories
Affinity DataIC50: 35nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University of Baroda
Curated by ChEMBL
The M.S. University of Baroda
Curated by ChEMBL
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R and Abbott Laboratories
Globe Pharmaceutical R and Abbott Laboratories
Affinity DataIC50: >1.00E+4nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair