BDBM134453 US8846658, 172

SMILES CN(C)Cc1ccc2oc(C(=O)Nc3ccc(F)c(c3)[C@@]3(COCC(N)=N3)C(F)F)c(C)c2c1

InChI Key InChIKey=JOOYEPMWNZTNNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134453   

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134453(US8846658, 172)
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent