BDBM13464 N-(3-{3-oxo-3-[7-(sulfoamino)-1,2,3,4-tetrahydroisoquinolin-2-yl]propyl}phenyl)sulfamic acid::Tetrahydroisoquinoline (TIQ) deriv. 12

SMILES OS(=O)(=O)Nc1cccc(CCC(=O)N2CCc3ccc(NS(O)(=O)=O)cc3C2)c1

InChI Key InChIKey=FXQBEIAXSVCANH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13464   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13464(N-(3-{3-oxo-3-[7-(sulfoamino)-1,2,3,4-tetrahydrois...)
Affinity DataIC50: 2.60E+4nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed