BDBM135104 US8846657, 1.3

SMILES C[C@@H](Nc1nc(cc2nc(-c3cccc(C)c3)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O)C1CCC1

InChI Key InChIKey=UUYMJIITKWMGPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 135104   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135104BDBM135104(US8846657, 1.3)
Affinity DataIC50: 122nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 135104BDBM135104(US8846657, 1.3)
Affinity DataIC50: 122nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2015
Entry Details
US Patent