BDBM136195 US8853193, 23-4
SMILES CNC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c2c1C
InChI Key InChIKey=WNQMRKSSTFTLSE-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 136195
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair