BDBM136553 US8865701, 77::US9505739, 77

SMILES Clc1ccc2c(CCC[C@]22CNC[C@H]2C(=O)N2CCC3(CC2c2ccccc2)C=Cc2ccccc32)n1

InChI Key InChIKey=ZLADFTQKDXFOSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136553   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136553(US8865701, 77 | US9505739, 77)
Affinity DataIC50: 200nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136553(US8865701, 77 | US9505739, 77)
Affinity DataIC50: 200nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details
US Patent