BDBM136561 US8865706, 29

SMILES NC1=N[C@]2(CO[C@H](C[C@H]2CS1)c1cncc(F)c1)c1ccc(F)cc1F

InChI Key InChIKey=WWPKMTNUNPCENN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136561   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM136561(US8865706, 29)
Affinity DataIC50: 37.9nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent