BDBM136581 US8865706, C89

SMILES Cc1cnc(cn1)[C@@H]1C[C@@H]2CSC(N)=N[C@@]2(CO1)c1ccc(F)cc1F

InChI Key InChIKey=VHXQPAJVUGIRHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136581   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM136581(US8865706, C89)
Affinity DataIC50: 3.62E+4nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent