BDBM136696 US8865686, Table 1, Compound 8

SMILES CN(C)C1C2CC3C(C(=O)c4c(O)cccc4C3(C)O)=C(O)C2(O)C(=O)C(C(=O)NC2C3SC(C)(C)C(N3C2=O)C(O)=O)=C1O

InChI Key InChIKey=IUSRGPJFZHYVEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136696   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
The United States of America, As Represented By The Secretary, Dept. of Health and Human Services

US Patent
LigandPNGBDBM136696(US8865686, Table 1, Compound 8)
Affinity DataIC50: 1.41E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent