BDBM136860 US8865911, 96::US8865911, 97 Isomer 1

SMILES COCc1cc(cc(c1)-c1ccc2C[C@@]3(CC[C@@H](CC3)OC)C3(N=C(C)C(N)=N3)c2c1)C#N

InChI Key InChIKey=WXWZQOAPXMLOGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136860   

TargetBeta-secretase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM136860(US8865911, 97 Isomer 1 | US8865911, 96)
Affinity DataIC50: 3.10nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM136860(US8865911, 97 Isomer 1 | US8865911, 96)
Affinity DataIC50: 6.10nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent