BDBM136869 US8865911, 106

SMILES COc1cc(cc(c1)-c1ccc2C[C@@]3(CC[C@@H](CC3)OC(F)F)[C@]3(N=C(C)C(N)=N3)c2c1)C#N

InChI Key InChIKey=DZGFZIMDVXHKMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136869   

TargetBeta-secretase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM136869(US8865911, 106)
Affinity DataIC50: 1nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent