BDBM137039 US8871790, 105

SMILES Cc1cc(C)c(cc1C(=O)N1CCC(F)(CC1)c1ccc(cc1)C#N)-c1nc2cc(ncc2[nH]1)N1CCCC1

InChI Key InChIKey=RFOZEMJEVLXDII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 137039   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM137039(US8871790, 105 | US20250017938, Compound 001-105)
Affinity DataIC50: 15nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM137039(US8871790, 105 | US20250017938, Compound 001-105)
Affinity DataIC50: 15nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent