BDBM137818 US8871934, 411

SMILES OCCn1cc(cn1)-c1cccc2c1-c1ccccc1C2(O)C(F)(F)F

InChI Key InChIKey=VNHRKDSDAJWKHJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 137818   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Japan Tobacco

Curated by ChEMBL

LigandBDBM137818(US8871934, 411)Copy SMILESCopy InChI

Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant PDHK2 assessed as residual PDH activity in presence of ATP using sodium pyruvate/Coenzyme A/thiamine pyrophosphate as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2025
Entry Details
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Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Human)
Japan Tobacco

Curated by ChEMBL

LigandBDBM137818(US8871934, 411)Copy SMILESCopy InChI

Affinity DataIC50: 66nMpH: 8.0 T: 2°CAssay Description:The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/6/2015
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL