BDBM137856 US8871934, 449::US8871934, 504

SMILES Cn1cc(cn1)-c1cc(OCCCC(O)=O)cc2c1-c1ccccc1C2(O)C(F)(F)F

InChI Key InChIKey=MLQBSJLQJIDSTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 137856   

LigandPNGBDBM137856(US8871934, 504 | US8871934, 449)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

LigandPNGBDBM137856(US8871934, 504 | US8871934, 449)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant PDHK2 assessed as residual PDH activity in presence of ATP using sodium pyruvate/Coenzyme A/thiamine pyrophosphate as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM137856(US8871934, 504 | US8871934, 449)
Affinity DataIC50: 47nMpH: 8.0 T: 2°CAssay Description:The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent