BDBM13803 2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4-oxo-1H,4H,5H-imidazo[4,5-d]pyridazin-1-yl]methyl}benzonitrile::Xanthine mimetic compound 18

SMILES Cn1ncc2n(Cc3ccccc3C#N)c(nc2c1=O)N1CCCC(N)C1

InChI Key InChIKey=LBOOXTLFQGNNED-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13803   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM13803(2-{[2-(3-aminopiperidin-1-yl)-5-methyl-4-oxo-1H,4H...)
Affinity DataKi:  260nM ΔG°:  -8.89kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2007
Entry Details Article
PubMed