BDBM138212 US8871778, 198

SMILES Cc1nn(cc1CN1CC[C@@H](O)C1)-c1cccc(Nc2ccc3n(C)cc(C(=O)C(F)(F)F)c3c2)n1

InChI Key InChIKey=QIYGHNDMIXXLHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138212   

TargetTyrosine-protein kinase SYK(Human)
Genosco

US Patent
LigandPNGBDBM138212(US8871778, 198)
Affinity DataIC50: 0.100nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Genosco

US Patent
LigandPNGBDBM138212(US8871778, 198)
Affinity DataIC50: 502nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent