BDBM138214 US8871778, 231

SMILES Cc1nn(cc1CN1C[C@H](O)C[C@H]1C(O)=O)-c1ccnc(Nc2ccc3n(C)c(C)c(Cl)c3c2)n1

InChI Key InChIKey=HKQWRPBPKJYWBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138214   

TargetTyrosine-protein kinase SYK(Human)
Genosco

US Patent
LigandPNGBDBM138214(US8871778, 231)
Affinity DataIC50: 13nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Genosco

US Patent
LigandPNGBDBM138214(US8871778, 231)
Affinity DataIC50: 9.46E+3nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
US Patent