BDBM139044 US8883784, 5

SMILES CN(C)CCCNc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1nc(ccc1CCCc1ccccc1)N1CCc2cccc(C(=O)Nc3nc4ccccc4s3)c2C1

InChI Key InChIKey=VWFWTVRQZACHLI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139044   

TargetBcl-2-like protein 1(Human)
Abbvie

US Patent
LigandPNGBDBM139044(US8883784, 5)
Affinity DataKi:  48nM ΔG°:  -9.98kcal/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent