BDBM139066 US8883771, 12

SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)N[C@@H]1CCCc2ccccc12)C(=O)Nc1ccc(Cc2ccc(NC(=O)N3CC[C@H]4CC[C@H](N4C(=O)[C@H](C3)NC(=O)[C@H](C)NC)C(=O)N[C@@H]3CCCc4ccccc34)cc2)cc1

InChI Key InChIKey=RGGJVNBMMNQZIB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139066   

TargetE3 ubiquitin-protein ligase XIAP(Human)
University of Michigan

US Patent
LigandPNGBDBM139066(US8883771, 12)
Affinity DataIC50: 10nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
University of Michigan

US Patent
LigandPNGBDBM139066(US8883771, 12)
Affinity DataIC50: 100nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2(Human)
University of Michigan

US Patent
LigandPNGBDBM139066(US8883771, 12)
Affinity DataIC50: 100nMpH: 7.5Assay Description:Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent