BDBM139106 US8614220, A51B1C3Z

SMILES CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2ncc3CCc4c(nn(C)c4-c3n2)C([O-])=O)c1

InChI Key InChIKey=QROBXWMBDYEVNI-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139106   

TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM139106(US8614220, A51B1C3Z)
Affinity DataIC50: 10nMpH: 7.9Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent