BDBM139452 US8614195, 2

SMILES CCc1ccc(cc1Cc1ccc2OCCOc2c1)[C@@H]1O[C@H](COC(=O)[C@H](N)C(C)C)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=SUHGYTPTNGVBFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139452   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM139452(US8614195, 2)
Affinity DataIC50: 17.5nMAssay Description:The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Novartis

US Patent
LigandPNGBDBM139452(US8614195, 2)
Affinity DataIC50: 35nMAssay Description:The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent