BDBM139461 US8614195, 3a

SMILES CCOP(=O)(OCC)OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C2CC2)c(Cc2ccc3OCCOc3c2)c1

InChI Key InChIKey=BTVYADHPHXYDQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139461   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM139461(US8614195, 3a)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Novartis

US Patent
LigandPNGBDBM139461(US8614195, 3a)
Affinity DataIC50: 5.65E+3nMAssay Description:The ability of the substances to inhibit the SGLT-2 activity may be demonstrated in a test set-up in which a CHO-K1 cell line (ATCC No. CCL 6 1) or a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent