BDBM139671 US8894989, 53

SMILES O=c1[nH]nc2[nH]c(CN3CCN(CC3)S(=O)(=O)c3ccccc3)nc3cccc1c23

InChI Key InChIKey=FBRRYYLADVWKMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139671   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandPNGBDBM139671(US8894989, 53)
Affinity DataIC50: 23nMpH: 8.0Assay Description:A convenient method to determine IC50 of a PARP inhibitor compound is a PARP assay using purified recombinant human PARP from Trevigan (Gaithersburg,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2015
Entry Details
US Patent