BDBM139984 US8901115, 133

SMILES COC(=O)Nc1ccc-2c(NC(=O)[C@H](C)CCC[C@H](N3CCC(OC3=O)c3c(F)c(Cl)ccc3C(F)(F)F)c3cc-2ccn3)c1

InChI Key InChIKey=SWSGHGVAWHIRMT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139984   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM139984(US8901115, 133)
Affinity DataKi:  69.3nM ΔG°:  -9.76kcal/moleT: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent