BDBM140063 US8901315, 106::US8901315, 107

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1

InChI Key InChIKey=ISQKDGBSKUJRSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 140063   

LigandPNGBDBM140063(US8901315, 107 | US8901315, 106)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

LigandPNGBDBM140063(US8901315, 107 | US8901315, 106)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPhosphodiesterase(Mouse)
Daiichi Sankyo

US Patent
LigandPNGBDBM140063(US8901315, 107 | US8901315, 106)
Affinity DataIC50: 1.20E+3nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPhosphodiesterase(Mouse)
Daiichi Sankyo

US Patent
LigandPNGBDBM140063(US8901315, 107 | US8901315, 106)
Affinity DataIC50: 2.00E+3nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent