BDBM140083 US8901315, 159::US8901315, 365::US8901315, 366

SMILES Cc1nn(C2CCCCC2)c2sc(cc12)C(=O)Nc1ccc(N2CCC(O)CC2)c(F)c1

InChI Key InChIKey=QYHFUBZVWDZWRK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 140083   

LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPhosphodiesterase(Mouse)
Daiichi Sankyo

US Patent
LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 1.60E+3nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPhosphodiesterase(Mouse)
Daiichi Sankyo

US Patent
LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 3.60E+3nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent

TargetPhosphodiesterase(Mouse)
Daiichi Sankyo

US Patent
LigandPNGBDBM140083(US8901315, 366 | US8901315, 365 | US8901315, 159)
Affinity DataIC50: 3.90E+3nMpH: 6.5 T: 2°CAssay Description:The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent