BDBM140220 US8906911, 29

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1C[C@H]2CCC[C@]2(C1)C(=O)N1C[C@@H]2C[C@H]1CN2c1cccc(OC(F)(F)F)c1

InChI Key InChIKey=CWIIAIOYSKNGAV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140220   

TargetC-C chemokine receptor type 2(Human)
Abbvie

US Patent
LigandPNGBDBM140220(US8906911, 29)
Affinity DataKi:  473nM ΔG°:  -8.02kcal/mole IC50: 148nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed in CHO cells expressing human CCR2B and Galpha ±16 coupling protein. All compounds were dissolved in DMSO a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2015
Entry Details
US Patent