BDBM140989 US8916574, Compound 6

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CNS(=O)(=O)C(F)(F)F)o3)cc2Cl)c1

InChI Key InChIKey=MVVFGYFCZLTASL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140989   

TargetEpidermal growth factor receptor(Human)
Qilu Pharmaceutical

US Patent
LigandPNGBDBM140989(US8916574, Compound 6)
Affinity DataIC50: 32.4nMT: 2°CAssay Description:In vitro kinase analysis was performed by using HTScan EGF Receptor Kinase Assay Kit (#7909) and HTScan HER2/ErbB2 Kinase Assay Kit (#7058) from Cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent