BDBM141006 BDBM435492::US8916576, 211

SMILES CCCC(=O)Oc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1

InChI Key InChIKey=WZWBQRCMIMNTNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141006   

TargetRho-associated protein kinase 2(Human)
Surface Logix

US Patent
LigandPNGBDBM141006(US8916576, 211 | BDBM435492)
Affinity DataIC50: 129nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Surface Logix

US Patent
LigandPNGBDBM141006(US8916576, 211 | BDBM435492)
Affinity DataIC50: 130nMAssay Description:ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
US Patent