BDBM141317 US8653304, 46b::US8653304, 47b

SMILES COc1c(NC(=O)N[C@@H]2Cc3ccccc3[C@@H]2O)cc(cc1[C@@H](O)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=WXEFOAJGNDYKQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141317   

TargetMitogen-activated protein kinase 14(Human)
Toray Industries

US Patent
LigandPNGBDBM141317(US8653304, 47b | US8653304, 46b)
Affinity DataIC50: 15nMT: 2°CAssay Description:Using human p38 MAPK alpha , the p38 MAPK inhibitory activity of Compound (I) was studied by a method partially modified from the method described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Toray Industries

US Patent
LigandPNGBDBM141317(US8653304, 47b | US8653304, 46b)
Affinity DataIC50: 18nMT: 2°CAssay Description:Using human p38 MAPK alpha , the p38 MAPK inhibitory activity of Compound (I) was studied by a method partially modified from the method described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent