BDBM141326 US8916577, 67

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3CCCc4c(nn(C)c4-c3n2)C(N)=O)cc1

InChI Key InChIKey=ACMMEMWMPLSEFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141326   

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141326(US8916577, 67)
Affinity DataIC50: 1.20E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141326(US8916577, 67)
Affinity DataIC50: 2.45E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141326(US8916577, 67)
Affinity DataIC50: 3.60E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent