BDBM141383 US8916600, 17::US9738632, Example 17

SMILES C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)NCc1ccccc1)c1ccc2COCOc2c1

InChI Key InChIKey=WMNUETGUHAWZSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141383   

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM141383(US8916600, 17 | US9738632, Example 17)
Affinity DataIC50: 0.996nMAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetGlucocorticoid receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM141383(US8916600, 17 | US9738632, Example 17)
Affinity DataIC50: 0.996nMpH: 7.4 T: 2°CAssay Description:In the GR radioligand binding assay, test compounds were serially diluted in semi-log steps (10 concentrations) with a final concentration of 10 uM. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent