BDBM141520 US8921373, 6::US9365563, 206::US9878991, Compound 206

SMILES Fc1ccc2nc(NC(=O)N3CCC(F)(CC3)c3ncccc3Cl)sc2c1

InChI Key InChIKey=LZCBHOVWHJDTEW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 141520   

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 508nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 508nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 508nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 1.46E+3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 1.46E+3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

LigandPNGBDBM141520(US8921373, 6 | US9365563, 206 | US9878991, Compoun...)
Affinity DataIC50: 1.46E+3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
US Patent