BDBM141872 US8921410, Table 1 Compound 41

SMILES Cc1cc(F)c(o1)C(=O)N1CC2CNCC2C1

InChI Key InChIKey=ZBKNVHICMHEOLA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141872   

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandPNGBDBM141872(US8921410, Table 1 Compound 41)
Affinity DataKi:  14nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

LigandPNGBDBM141872(US8921410, Table 1 Compound 41)
Affinity DataKi:  65nM ΔG°:  -9.67kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent