BDBM141879 US8921410, Table 2 Compound 12

SMILES Cc1nocc1C(=O)N1CC2CNCC(C2)C1

InChI Key InChIKey=DYQGFRKOIIPELX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141879   

LigandPNGBDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  9.5nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent

TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
Targacept

US Patent
LigandPNGBDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  21nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent