BDBM142371 US8933221, 12::US8933221, 23::US8933221, 24

SMILES NC1=N[C@]2(COCC[C@H]2CS1)c1ccccc1F

InChI Key InChIKey=WTXBHLMRVJGNPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 142371   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM142371(US8933221, 24 | US8933221, 23 | US8933221, 12)
Affinity DataIC50: 4.54E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM142371(US8933221, 24 | US8933221, 23 | US8933221, 12)
Affinity DataIC50: 7.95E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM142371(US8933221, 24 | US8933221, 23 | US8933221, 12)
Affinity DataIC50: 7.95E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent