BDBM142384 US8933221, 25

SMILES NC1=N[C@]2(COCC[C@H]2CS1)c1ccccc1OC(F)(F)F

InChI Key InChIKey=TTZTYQQZJBBUDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142384   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM142384(US8933221, 25)
Affinity DataIC50: 8.79E+4nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent