BDBM142391 US8933221, 1

SMILES c1cc(c(cc1F)F)[C@]23COCC[C@H]2CSC(=N3)N

InChI Key InChIKey=CUNQNADGWRXYCV-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142391   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM142391(US8933221, 1)
Affinity DataIC50: 6.70E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
US Patent