BDBM142619 US8933228, 10

SMILES COc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)n(C)c34)c3ccccc23)cc1

InChI Key InChIKey=GRFBNEAPKLWFPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142619   

TargetTyrosine-protein kinase HCK(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142619BDBM142619(US8933228, 10)
Affinity DataIC50: 3nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142619BDBM142619(US8933228, 10)
Affinity DataIC50: 6nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142619BDBM142619(US8933228, 10)
Affinity DataIC50: 7nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetMitogen-activated protein kinase 12(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 142619BDBM142619(US8933228, 10)
Affinity DataIC50: 45nMAssay Description:The enzyme inhibitory activity of test compounds was determined by fluorescence resonance energy transfer (FRET) using synthetic peptides labelled wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent