BDBM142753 US8937193, 6e

SMILES Cc1c(-c2c(C)c(=O)c3c(CCc4ccccc4)c(O)c(O)cc3c2=O)c(=O)c2cc(O)c(O)c(CCc3ccccc3)c2c1=O

InChI Key InChIKey=IVBKZDLBSIWCDU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142753   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM142753(US8937193, 6e)
Affinity DataIC50: 1.29E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM142753(US8937193, 6e)
Affinity DataIC50: 1.79E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetApoptosis regulator Bcl-2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM142753(US8937193, 6e)
Affinity DataIC50: 2.57E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetBcl-2-related protein A1(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM142753(US8937193, 6e)
Affinity DataIC50: 9.72E+3nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent