BDBM142800 US8940736, 184

SMILES CN1CCN(CC(=O)N[C@@H]2CCN(C[C@H]2O)c2cc(cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)C#N)CC1

InChI Key InChIKey=QTVVJUCRUNTSEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142800   

TargetCasein kinase II subunit alpha'(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142800(US8940736, 184)
Affinity DataIC50: 0.640nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM142800(US8940736, 184)
Affinity DataIC50: 1.37nMpH: 7.4 T: 2°CAssay Description:The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
US Patent