BDBM144331 US8969336, 575

SMILES CN1CCN(CC1)C1CCN(CC1)c1ccc(Nc2nc(N[C@H]3CC[C@H](O)CC3)c(Cl)nc2C(N)=O)cc1C

InChI Key InChIKey=OZHDGGPIVQKPDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 144331   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM144331(US8969336, 575)
Affinity DataIC50: 0.720nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Astellas Pharma

US Patent
LigandPNGBDBM144331(US8969336, 575)
Affinity DataIC50: 1.30nMAssay Description:A partial protein of only a kinase domain of RET protein was purchased from Carna Biosciences Inc., Japan. The phosphorylation activity toward a pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Astellas Pharma

US Patent
LigandPNGBDBM144331(US8969336, 575)
Affinity DataIC50: 1.60nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent