BDBM144418 US8969376, 1.175

SMILES Cc1nc2ccc(F)cc2nc1-c1cc2nc(cc(N[C@H]3CC[C@@](C)(O)CC3)n2n1)N1CC[C@H](F)C1

InChI Key InChIKey=FOHXAFIDDJBWDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144418   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM144418(US8969376, 1.175)
Affinity DataIC50: 0.120nMpH: 8.0Assay Description:The PDE assay was performed according to a modified method referred to a report of Kotera et al. (Kotera et al., Biochem. Pharmacol., vol. 60, pp. 13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent