BDBM144447 US8969394, 26

SMILES Cc1sc(C)c(C(=O)NC2(CC2)c2ccc(cc2)-c2nn[nH]n2)c1Cc1cccc(c1)C(F)(F)F

InChI Key InChIKey=CIEAOSWNZSOPSF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144447   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Canada

US Patent
LigandPNGBDBM144447(US8969394, 26)
Affinity DataKi:  0.700nM ΔG°:  -12.5kcal/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent